What are Needle-Free Injections?

Needle-free injection is a method of injecting using a jet injector device like Comfort-in™, which injects liquid medicine, anaesthesia, vitamins, or other liquid injectables through the skin and into the subcutaneous tissue, via high pressure. Injections with jet-injectors preserve tissue and prevent lipodystrophy (lumps/small dents on the skin when injections are repeatedly performed at the same spot).

What is the Comfort-in™?

Comfort-in™ is a no-needle injection system for the subcutaneous administration of medication. It injects liquid through the skin and into the subcutaneous tissue via high-pressure, at a speed of 100 metres per second. The Comfort-in™ is the most versatile injector on the market (that we know of), because it can be used for injecting almost any injectable liquid including insulin, anaesthesia, vaccines, growth hormones, sports medicines, medicine for ED, vitamins such as B12, and so much more.

What are the advantages of Comfort-in™?

The Comfort-in™ injection system has many advantages such as:

  • needle-free injection
  • virtually painless
  • reduces tissue damage and scar tissue
  • reduces psychological inhibitions and fears
  • minimises injection-induced stress
  • elimination of injury to patient and physician caused by needle
  • safe and easy use
  • most economical on the market, being good for up to 10,000 injections

What do I need to start needle-free injections?

You just need the basic equipment included in a Comfort-in™ injection kit, which includes:

  • 1 Comfort-in™ injector
  • 1 Comfort-in™ pressure lever
  • 1 Portable pouch
  • 8 sterilised syringes
  • sterilised adapters
  • instructional manual

How does the Comfort-in™ work?

Liquid medications are transferred into the needle-free nozzle/syringe via adapters. There are 5 different adapters available to suit all types of injectable liquid from any type of pen, vial or cartridge. The needle-free nozzle/syringe can contain up to 0.5ml per single injection. After loading the injector, the liquid medication in the nozzle/syringe is propelled effortlessly as a small jet into the body via a spring-action.

The liquid medication disperses into the subcutaneous tissue via the path of least resistance, in a cone-like shape. There are no sharp needles penetrating through delicate skin and tissue. This reduces the likelihood of tissue damage, the formation of scar tissue and the chance of developing lipohypertrophy (lumps under the skin caused by multiple injections in the same area of skin over an extended period of time or re-using the same needle without correct sterilisation). This is a common issue for sufferers of Type 1 Diabetes.

The Comfort-in™ needle-free injection is fast, safe, quickly absorbed by the body and ‘virtually’ painless.

How should the user be prepared for Injecting with the needle-free injector?

The person receiving the injection should be informed about the release noise of the injector to prevent defensive arm movement or startled reflex. Everybody is different and has a different sensitivity level. You can expect to feel absolutely nothing or a small flick like sensation. Also depending on the medication being injected, you may also feel a stinging sensation.

The injector button will not depress. What could be the cause?

In order to depress the injector button the spring of the main unit must be activated. To prepare the injection system for use, insert the injector’s pressure stick into the opening of the injector head. Push down on the handle of the pressure lever until you hear a click sound. Then remove the injector from the lever.

Is the injection with Comfort-in™ painless?

When correctly applied, the injection with Comfort-in™ is virtually painless. The sensation can be described as a short slight pressure on the skin surface. Since pain is felt individually one cannot state a general and obliging assertion. As fluid is pressed under the skin the patient will sense the injection with Comfort-in™ more or less, depending on the volume and the individual sensitivity. Users generally assess the sting from a needle as more unpleasant than the injection with Comfort-in™.

Can the syringes be used again?

In order to guarantee sterility and function, the syringes are intended to be used once only. However, some individuals will wash and sterilise the syringes them for reuse the same day, if they are taking multiple shots in one day.

What are the adapters for?

The adapters are for the transfer of liquid drugs from conventional medicine containers into the syringe of the Comfort-in™ system.

Up to now, conventional medicine containers are designed for injection by needle (cannula), e.g. pen cartridges, piercing of injection vials or snap-off ampules. As Comfort-in™ has no needle, the Comfort-in™ team have developed special adapters to transfer the drug from medicine containers into the Comfort-in™ syringes.

How many times can an adapter be used?

The adapter is a disposable product intended to be used one one medication vial. Sterility is not guaranteed for multiple use, so never use the same Adapter for more than one medication vial.

How deep does the medication penetrate the skin?

The pressure and speed are calculated in such a way that the medicine only enters into the subcutaneous adipose tissue. The depth of penetration also depends on the applied volume, it reaches from 2.5 to 6 mm.

Is it recommended to change the injection site?

Yes, the injection site should be changed in the same way as with a conventional syringe.

How should the patient be positioned for injecting with the Comfort-in™?

The patient should be sitting upright in a relaxed position. The time between positioning and releasing the injector should be kept as brief as possible especially with children and resless patients.

Is the Comfort-in™ licensed?

In many countries, the Comfort-in™ is licensed by the proper authorities. CE certified, by Health Canada, Australia and the United Kingdom.

Is bleeding possible?

Bleeding does not usually occur. Occasionally, a pin-sized drop of blood may appear at the needle-free injection site. This is the entry point where the liquid enters the body via high pressure. It is usually caused by the rupture of capillaries (small blood vessels). Clean the area with antiseptic. This is more likely to occur if the user has been taking medication to treat cardiovascular disease or normal aspirin for pain relief.

Does residual medication remain on the skin?

If this occurs, not all of the medication has been administered as part of it remains on the skin. Residual medicine on the skin is caused by the Comfort-in™ not being placed firmly enough on the skin or not being applied vertically. Please ensure the next time that the Comfort-in™ is placed on the skin firmly and vertically. Press the injector firmly onto the injection site until the skin is clearly dented and the syringe tip is completely enclosed by the skin. It is important that a firm seal is formed between the orifice of the syringe and the skin so that the medication can pass into the body without leakage. Only firm pressure and correct positioning can achieve this.

  • Keep the syringe pressed against the skin for 5 seconds after completing the injection.
  • Increase the pressure in the main body of the injection device by 5.
  • For any other enquiries, please contact your seller directly.

What are the minimum and maximum quantities of medication that can be administered per application?

A minimum of 0.01 ml and a maximum of 0.5 ml of a liquid drug can be administered using Comfort-in™

Can needle-free injections cause bruising?

Needle-free injections are still injections, and if not done correctly or in certain situations they can still cause bruising. With practice,  you will get better, and learn to avoid the situations that might contribute to bruising.

  1. Always avoid injecting over blood vessels (capillaries and veins).
  2. Before injection, please read the user manual and instructions, and follow directions.
  3. Watch our instructional videos to learn how to inject properly.
  4. Make sure to create a seal around the tip of the syringe/nozzle. The top must be at a 90 degrees angle to the “injection site” and apply the maximum comfortable pressure.
needle vs jet injector

Injecting with a needle vs. injecting with a jet injector.